The specific cases are as follows: 1. If you have had syphilis 2 years ago and have undergone the complete process of penicillin antisepsis treatment, you can get pregnant and test the syphilis antibody titer during pregnancy. 2, had syphilis but did not go through the complete process of penicillin treatment, it is recommended to go through the complete process of penicillin treatment before pregnancy. 3.Recently found positive syphilis antibody, do not know when the disease, it is recommended to carry out the complete process of penicillin anti-syphilis treatment before pregnancy. 4.It is recommended that the couple should be investigated and treated together.