Dapoxetine and sildenafil can only be taken at the same time if both erectile dysfunction and premature ejaculation are present, and should be taken under the supervision of a doctor. Dapoxetine is a potent selective 5-hydroxytryptamine reuptake inhibitor, suitable for the treatment of premature ejaculation and poor ejaculatory control in men; while sildenafil is an oral phosphodiesterase type 5 inhibitor, suitable for the treatment of erectile dysfunction in men. Dapoxetine and sildenafil should only be taken together if both of these conditions are present. It should be noted that Dapoxetine is prohibited for use in people with known hypersensitivity to Dapoxetine hydrochloride or any excipients, people with heart failure, people with moderate and severe liver injury, etc.; patients may experience adverse reactions such as headache, dizziness and nausea after taking it. Sildenafil is forbidden to be used in combination with nitrate drugs, and this drug is contraindicated in women, people who are allergic to this product, children, and people whose recent cardiovascular status makes sexual intercourse inappropriate. And patients may experience headache, dizziness, nasal congestion and other adverse reactions after taking it. It is recommended that patients should use Dapoxetine and Sildenafil under the guidance of a doctor, do not use it without authorization to avoid delay.