Tacrolimus take how long can stop need to follow the doctor’s instructions, due to the different specific conditions of patients, stopping time varies greatly, there is no specific data to support. Tacrolimus can be used to prevent graft rejection after liver or kidney transplantation, and to treat graft rejection after liver or kidney transplantation that cannot be controlled by other immunosuppressive drugs, and the discontinuation of tacrolimus should be in accordance with the doctor’s instructions, and should not be discontinued without authorization. Adverse reactions such as anemia, thrombocytopenia, leukocytosis, hypertension, diabetes mellitus, anorexia, insomnia, depression, tremor, impaired consciousness, eye irritation, dullness of hearing, tachycardia, pruritus, rash, alopecia, acne, hyperhidrosis, arthralgia, renal injury, dysmenorrhea, and uterine bleeding may occur with the use of this product. Prompt medical attention is recommended in case of adverse reactions. It is contraindicated in pregnant and lactating women, those who are allergic to tacrolimus or other macrolides, and those who are hypersensitive to this product. Patients taking Tacrolimus are advised to go to regular hospitals, consult a professional doctor, cooperate with the doctor to complete the relevant examinations, and avoid blindly stopping the drug.