Liver shrinkage cannot be cured by itself. Liver shrinkage may be caused by cirrhosis, acute liver failure, hepatocellular carcinoma, portal vein compression, viral hepatitis, primary biliary cirrhosis, autoimmune liver disease and so on. Once liver shrinkage occurs, it is difficult to be cured by oneself. If not treated in time, the patient will have many discomforts, and it may threaten the life span. The cause of liver shrinkage should be clarified, and according to the cause of the disease, the right program should be given to treat the symptoms, slow down the process of liver shrinkage, avoid further shrinkage of the liver, stop the development of the disease, and reduce the impact of the disease on the body. If the disease is in the advanced stage of liver failure, liver transplantation is recommended. It is recommended to go to regular hospitals in time when you find the symptoms of liver shrinkage and standardize the treatment.