If the widening of the renal pelvis in adults is caused by physiological factors such as holding urine for a long time, it is generally not serious; however, if it is caused by pathological conditions such as urinary stones, renal tumors, and urinary tract infections, it is relatively serious. 1. Physiological factors: such as holding urine for too long can also lead to widening of the renal pelvis, the urine can be discharged after the general return to normal, the remaining no other discomfort symptoms, such cases do not need to worry too much, regular review can be. 2. Urinary stones: Stones in the kidney, bladder, ureter and urethra can burden the kidneys and prevent excess water from being discharged in time, which in turn leads to widening of the renal pelvis. Patients can follow the doctor’s instructions to take medicines such as stone removal granules to relieve the problem. 3. Kidney tumor: Kidney tumor can also lead to kidney function damage, which may lead to widening of renal pelvis. Patients should get timely treatment after discovery, and usually need to undergo surgery to remove the tumor. 4. Urinary system infection: it refers to the inflammatory reaction caused by bacterial invasion, which will increase the burden of kidney, and even lead to widening of renal pelvis due to fluid accumulation. Patients can take levofloxacin and other medications as prescribed by doctors for treatment. The above medication should follow the doctor’s prescription, and should not be used without authorization, so as to avoid aggravation of the condition. Adults with widened renal pelvis of 16mm are recommended to go to regular hospitals for timely examination and targeted treatment.