Fever and headache are frequent symptoms of some infectious diseases. We can use warm water to rub the body, such as the armpits, groin, neck and other parts rich in blood vessels, or ice packs on the head, cold towels on the forehead and other physical cooling methods. If the effect is not good, you can take oral antipyretic and analgesic drugs, including ibuprofen, acetaminophen, or indomethacin, and of course, the commonly used compound Tylenol, etc. You can also administer the drugs through the anal route, and pay attention to hydration at the same time. Within 1-2 hours after the medication is administered, the fever can generally be reduced by sweating and the headache can be relieved. Because these drugs are antipyretic and anti-inflammatory drugs, they are not only effective for fever but also for headache. The above measures are only symptomatic treatment, but clinically we have to determine whether the infection is bacterial or viral, and perform blood tests, throat swabs, and sputum cultures to observe any abnormalities. If the fever is caused by viral infection, first of all we have to carry out antiviral treatment, such as giving oseltamivir capsules antiviral or Lianhua Qingfei capsules antiviral treatment; if the fever is caused by bacteria, we give antibiotics, such as penicillin, cephalosporins and other antibiotics antibacterial treatment, the headache caused by fever can be relieved. There are also some clinical headaches that are more severe and last longer, and probably will not be completely relieved as the body temperature drops, and then the possibility of encephalitis or meningitis should be considered. It is necessary to check the cerebrospinal fluid, cranial CT or MRI to clarify the presence of intracranial infection, and further treatment in hospital is required at this time.