As women age, ovarian reserve function (0R for short, refers to the potential of the ovaries to produce eggs in quantity and quality, indirectly reflecting ovarian function) gradually declines, a process that begins before birth, with 7×106 potential eggs in mid-pregnancy and nearly 85% of them at birth undergoing atresia. The decline continues throughout the reproductive years until near menopause, when less than 1000 primordial follicles remain. As we age, the number of follicles gradually decreases and the proportion of low-quality oocytes increases. Clinical assessment of ovarian reserve function 1. Age Ovarian function gradually declines as women age. The number of primordial follicles in a woman’s ovaries starts to decrease at an accelerated rate around the age of 36 until the woman is menopausal and there are basically no primordial follicles. The number of primordial follicles starts to decrease at an accelerated rate around the age of 36 until menopause, when there are basically no primordial follicles. However, each person is in a different environment and the actual depletion of ovarian function will be different. Therefore, age is an important criterion to assess the quantity and quality of eggs, but it can only be used as a reference to assess female fertility. 2. Blood indicators (1) Basal FSH, FSH/LH, Basal E2 Basal values, i.e. when blood is drawn on days 2 to 4 of the menstrual cycle: FSH>40 IU/L – ovarian function is depleted and there is almost no stock left; FSH>20 IU/L – insidious stage of premature ovarian failure; FSH>10-15 IU/L – low ovarian response; FSH/LH>2-3.6 – often indicates diminished ovarian reserve function E2>80 pg/ml- -suggests that the ovary has begun to enter an early stage of decline (2) Basal INH-B Basal INHB concentration decreases before FSH increases in women with declining ovarian reserve function, indicating that INHB is more sensitive in predicting ovarian reserve function. Basal INHB <45pg/ml indicates reduced ovarian reserve function. AMH is a regulator of follicular growth and development and is involved in two important recruitment processes in physiological follicle formation: initiating follicle recruitment and dominant follicle recruitment.AMH inhibits excessive follicular growth, prevents premature follicular depletion and preserves ovarian reserve function.AMH decreases with age.AMH <1.26ug/L has a sensitivity of 97% in predicting decreased ovarian reserve function and is highly suggestive of decreased ovarian reserve. The sensitivity of AMH <1.26ug/L in predicting decreased ovarian reserve is 97%, highly suggestive of decreased ovarian reserve. Ultrasound assessment of ovarian function is mainly achieved by measuring the sinus follicle count (AFC), ovarian size, and ovarian stromal blood flow (currently less commonly used). The basal sinus follicle count is the number of sinus follicles with a diameter of 2-9 mm detected on vaginal ultrasound during the early follicular phase. AFC<=5 - poor ovarian reserve, low ovarian response, increased IVF cycle cancellation rate; 5