Treatment of neonatal impetigo depends on the condition: in mild cases, mainly local medication is taken, if the condition is serious, it is necessary to cooperate with systemic medication. Newborn pustular rash, if the current symptoms are relatively mild, there are only a few scattered pustules, you can first use medical alcohol to disinfect the local area, and then use a sterilized needle to pick the pustules, discharge pus and apply antibiotic ointment, such as mupirocin ointment, erythromycin ointment and so on to promote anti-inflammatory. If the neonatal pustules are more serious, there are large areas of pus and bad spirits, in addition to local treatment, often need to be combined with systemic antibiotic drugs, such as oral penicillin V potassium, amoxicillin, etc., and some newborns need to be taken to the intravenous infusion treatment. Neonatal pustules should be timely consultation, with the doctor to take medication, the patient can not self-medication.