Heartburn is a common symptom of the digestive system. Whether or not heartburn will turn into cancer and how long it will turn into cancer depends on the disease and the specific condition of the patient, and cannot be generalized. Heartburn is a kind of burning pain located in the upper abdomen or lower chest, which may or may not be accompanied by acid reflux, and can be seen in gastroesophageal reflux disease (GERD), chronic gastritis, gastric ulcer and so on. 1. Gastroesophageal reflux: the clinical manifestations of patients are diverse, varying in severity, the most typical symptom is heartburn and acid reflux, which is mainly a burning sensation at the back of the sternum or the lower part of the xiphoid process. 2. Gastritis: the typical symptom of chronic gastritis is epigastric pain or discomfort, most patients with gastritis have epigastric pain or discomfort, usually the patient’s so-called heartburn, mainly due to excessive acid, resulting in localized burning sensation. 3. Gastric ulcer: gastric ulcer patients have more gastric acid secretion, when gastric acid secretion reaches a certain level, heartburn symptoms may occur. Gastric acid reflux erodes esophageal mucosa, causing damage to esophageal mucosal cells, which is prone to atypical hyperplasia, leading to the occurrence of esophageal cancer. Chronic gastritis and gastric ulcer may also develop into gastric cancer if not treated. If the disease is mild or treated in time, cancer may not occur. Therefore, heartburn may or may not be cancerous, and there is no definite data on the chance of cancer. When you feel uncomfortable symptoms such as heartburn and acid reflux, it is recommended to consult a doctor and take oral medication as prescribed by the doctor, as well as regular checkups to avoid cancerous changes.