Diabetic microangiopathy includes: 1, diabetic retinopathy, early patients can show hemorrhage and exudate, serious diabetic retinopathy can lead to retinal detachment, patients even blindness. 2, diabetic nephropathy, early patients can show elevated levels of urinary microalbumin, to the clinical stage of nephropathy will show a large amount of protein urine, to end-stage nephropathy patients will show elevated levels of creatinine. The patient will show an elevated creatinine level, and serious patients will be combined with uremia requiring dialysis treatment. 3, diabetic peripheral neuropathy, after the occurrence of diabetic peripheral neuropathy patients will mainly show numbness, pain, burning-like sensation in both lower limbs, to the late stage of the disease patients will show a significant loss of pain and temperature sensation, serious patients will appear diabetic foot ulcers, gangrene, and even require amputation.