Ichthyosis on the calf is often caused by microbial infection, genetic factors, etc. It can be improved by general care, topical medication as well as oral medication. 1. General care: if the patient does not have fungal, bacterial and other pathogenic infections, calf ichthyosis is only dry skin or physical irritation, can be improved through gentle cleaning of the skin, strengthen the skin sunscreen and moisturizing, eat more food rich in vitamin C, and wear comfortable skin-friendly clothes and pants to reduce skin friction. 2. Topical medication: If the patient has mild lichen planus or ichthyosis due to hormonal imbalance, fungal skin infection or genetic factors, he can use some ointment such as retinoic acid gel to improve the lesions, and then use ointment such as cod liver oil ointment to promote skin moisturizing. 3. Oral medication: For patients who have been using external medication for a period of time with poor results, or who have serious fungal infections and proliferation of skin symptoms, it is recommended that antifungal medications such as terbinafine and itraconazole should be taken systematically according to the course of treatment. The specific method of removing ichthyosis spots should be in the medical treatment, according to the doctor’s guidance for treatment, patients need to pay attention to should be under the guidance of the doctor to use drugs to avoid causing adverse reactions.