The treatment of urinary protein to negative eyes or swelling mainly depends on the cause of edema, according to the cause of targeted treatment. Clinical common causes of edema are nephrogenic edema, hepatic edema, cardiogenic edema, endocrine edema and so on. Therefore, it is not excluded that patients have edema due to other diseases in addition to renal diseases. 1. Nephrogenic edema: urinary protein negative eyes are still swollen, can be considered urinary protein symptoms have not completely disappeared, it is recommended to continue to use drugs such as furosemide and other anti-swelling treatment. 2. Hepatogenic edema: if cirrhosis of the liver can lead to edema, usually need to take hepatoprotective drugs such as polyene phosphatidylcholine, but also can be applied to diuretics such as furosemide to reduce swelling treatment. 3. Cardiogenic edema: common in right heart failure, constrictive pericarditis, etc. Diuretics such as furosemide can be applied to reduce edema. 4. Endocrine edema: such as hypothyroidism, etc., need to take oral levothyroxine sodium and other drugs to reduce swelling treatment. All of the above medications should be used under the guidance of a doctor to avoid self-medication. Urine protein is still swollen eyes may also have other reasons, it is recommended that patients go to the regular hospital in time to improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.