Gastrointestinal reactions to metformin are relatively common, however, attention to the way of taking can effectively reduce some. When taking it, try not to take it on an empty stomach or before meals, you can choose to take it during meals, which will effectively reduce the stimulation of the gastrointestinal tract, and you can try to choose extended-release tablets. Patients suffering from diabetes mellitus, if it is type 2 diabetes mellitus, first need to use metformin treatment regularly. At the same time, pay attention to dietary control, to achieve a low-fat, light diet, do not eat food with high sugar content, will help control blood sugar. To regularly visit the hospital for blood glucose and glycated hemoglobin tests, it is important to keep blood glucose control within the normal range, which can effectively reduce the complications of diabetes and improve the quality of life of patients.