The outcome of 50-year-old leiomyosarcoma larger than 5cm without surgery is related to the location of leiomyosarcoma growth, symptoms, menstrual situation and other factors, mainly divided into intermural leiomyosarcoma, submucosal leiomyosarcoma, subplasma leiomyosarcoma and so on. There may be no discomfort, or there may be malignancy, compression symptoms such as frequent urination, menstrual changes and so on. 1. Intermural leiomyoma: if the leiomyoma is larger than 5cm but not more than 10cm, usually there will be no abnormal performance, a few patients may have menstrual changes such as prolongation of menstruation, shortening of menstruation, increase in menstruation, etc. If the leiomyoma is more than 10cm, then it may also have pressure symptoms such as frequent urination, constipation, etc. 2. Submucous fibroid: if the fibroid exceeds 5cm without surgery, it is likely to show menstrual changes such as increased uterine secretion, prolonged menstrual period, increased menstrual flow, etc., and even anemia or hemorrhagic shock may occur, therefore, it is recommended to carry out surgery for uterine submucous fibroid regardless of its size in a timely manner. 3. Sub-plasma fibroid: fibroid larger than 5cm without surgery may have frequent urination and urgency, constipation and diarrhea and other symptoms. If the above symptoms occur, it is recommended to go to the hospital in time for early and regular treatment.