Patients with SLE may have hematologic involvement, and routine blood tests often indicate a decrease in the triple system, which is a decrease in white blood cells, red blood cells and platelets. Some patients with SLE may develop severe hemolytic anemia, which can also be seen as a significant decrease in hemoglobin, and reticulocytes are often significantly increased at this time, so patients with SLE should be alerted to the development of hemolytic anemia. After SLE patients develop hematologic involvement, they need to be treated with glucocorticoids to help the white blood cells, red blood cells and platelets rise, because there is a risk of infection after a decrease in white blood cells, and a decrease in platelets can lead to bleeding tendencies.