The rational application of sleeping drugs should pay attention to the following aspects: 1. First, we should determine the cause of insomnia to be treated etiologically, such as pain-induced insomnia, sleep can be improved after giving pain treatment. 2. Be familiar with the indications of drugs, such as zopiclone mainly for patients with difficulty in falling asleep, alprazolam mainly for patients with poor sleep quality, diazepam mainly for patients with early awakening. 3. The use of the drug is contraindicated, avoiding the combination with central inhibitors such as alcohol, caution in children, lactation and pregnant women is prohibited. 4, individualized medication. The application of sleeping pills has a principle of on-demand medication, short-term medication and intermittent medication, the use of the minimum effective amount, effective after the gradual reduction or discontinuation, avoid gradually increasing the dose to prevent dependence and tolerance. 5, for patients engaged in mechanical operations, driving and other fine work, be cautious in the administration of drugs. 6, immediately after taking drugs to bed to rest, to maintain a quiet state. 7, be alert to depression in patients with Suicidal tendency, avoid high doses of medication.