In general, waking up with cloudy blood in the mouth may be caused by oral diseases such as periodontitis, gingivoma, etc., or gastritis, gastric ulcer and other gastric diseases caused by upper gastrointestinal bleeding manifestations, you can take cephalosporin, metronidazole, growth inhibitors and other medications for treatment, and endoscopic hemostasis and other operations can be performed if necessary. 1. Oral diseases: such as periodontitis, gingival tumor or hemangioma metastasis to the gums caused by oral bleeding. Periodontitis can be treated with cephalosporin, metronidazole and other drugs; gingival tumor can be treated with injection of paxillin and gingivectomy; hemangioma can be treated with oral propranolol, injection of paxillin and other drugs. 2. Stomach diseases: such as gastritis, gastric ulcer, gastric cancer and other diseases can cause upper gastrointestinal bleeding, vomiting blood, black stool and other symptoms. Acid inhibitors such as lansoprazole and rabeprazole, gastric mucosal protectors such as aluminum thioglycollate and teprenone, growth inhibitors, prostaglandins and other drugs can be chosen for treatment. If necessary, endoscopic hemostasis, three-lumen two-bladder tube hemostasis and other operations can be carried out to stop bleeding. Waking up from sleep and vomiting cloudy blood in the mouth is recommended to consult a doctor in order to clarify the diagnosis and carry out targeted treatment. In addition, all of the above drugs should be taken under the guidance of a doctor and should not be used without authorization.