Anemia can cause abdominal pain, but it is very rare. This is because there is a cell in the blood called red blood cell, which is responsible for carrying oxygen to all the tissues and organs of the body. Once anemia occurs, a series of ischemic and hypoxic manifestations of the tissues and organs will occur due to a decrease in both red blood cell and hemoglobin values and a lack of oxygen. In the gastrointestinal tract, hypoxia may cause loss of appetite, diarrhea, abdominal distension, etc. In a few cases, abdominal pain may occur, usually due to ischemic enteropathy. This kind of abdominal pain is still relatively intense, and acute gastroenteritis and other causes of acute abdomen need to be excluded. If neither is present, there may be some relationship with the patient’s anemia. At this time, we should actively look for the cause of anemia, correct the patient’s symptoms of anemia, and the abdominal pain will be reduced, in addition the symptoms can disappear.