Gout patients with swollen and unbendable knees can be treated with non-steroidal anti-inflammatory drugs (NSAIDs) such as etoricoxib, colchicine and glucocorticoids such as prednisone.
1. Non-steroidal anti-inflammatory drugs: non-steroidal anti-inflammatory drugs can inhibit cyclooxygenase to reduce the synthesis of prostaglandins in the body so as to play an anti-inflammatory role in pain relief, can effectively relieve gout patients with swollen knees and can not bend the symptoms, the representative of the drug including etoricoxib, celecoxib and naproxen, etc, but the use of this type of drug treatment need to be vigilant about the risk of gastrointestinal tract.
2. Colchicine: Colchicine is an alkaloid with anti-inflammatory effects. Small doses of colchicine can effectively relieve the symptoms of joint pain, swelling and fever that occur in gouty attacks, and can be used in combination with non-steroidal anti-inflammatory drugs (NSAIDs) or glucocorticosteroids when necessary.
3. Glucocorticosteroids: representative glucocorticosteroids include betamethasone, methylprednisolone, prednisone, etc. Glucocorticosteroids can be used in patients with contraindications to NSAIDs and colchicine, or those who have been treated with these two drugs with poor results, or those who have renal insufficiency.
Drugs need to be used under the guidance of a physician, it is recommended that gout patients with symptoms of knee swelling and inability to bend to the rheumatology and immunology department of a regular hospital and other related departments for detailed consultation.