Treatment of group burns

  Group burns refer to more than 10 cases or more than 5 cases of severe burns caused by the same cause of injury at the same time. Most of them are caused by sudden accidents, and they are often accompanied by other injuries, which, together with the shortage of human, material and technical resources, can easily delay the rescue time and increase the difficulty of later treatment. Group burn patients, especially those with large burns and severe facial burns, often have combined respiratory burns. Respiratory tract injury, not only caused by the thermal effect of inhaled hot air or hot steam, but more importantly, caused by the inhalation of harmful fumes or irritating toxic chemicals and gases, which can directly damage the lung parenchyma in severe cases, and can absorb poisoning. This injury can affect respiratory function and cause impaired oxygenation and carbon dioxide expulsion. Therefore, the traditional names of respiratory burns and lung burns are now collectively referred to as inhalation injuries.  Inhalation injuries are more common. With the development of modern industry, people use a large number of chemical products in production and life, the incidence of inhalation injuries caused by the combustion of such products has increased significantly. Due to the development of anti-personnel weapons, the incidence of inhalation injuries will further increase in future wars. Inhalation injuries directly affect the gas exchange in the lungs, can produce progressive hypoxia, and aggravate acidosis. Because inhalation injury destroys the defense structure of the respiratory system, it creates the conditions for infection. Therefore, patients with inhalation injuries have a high incidence of shock and sepsis and are severely ill; there are many respiratory complications and early complication of cattle. The same area and depth of burn patients, combined with aspiration injury significantly higher mortality; the more severe the aspiration injury, the higher the mortality rate.  The diagnostic classification of inhalation injury and the course of disease staging have been discussed more, so this article will not be detailed. In the diagnosis and treatment of group burn patients must accurately determine the injury to take effective treatment measures to ensure patient life safety. In the treatment of inhalation injury, respiratory support techniques play an important role. Respiratory support technology is a field of clinical medicine that has made rapid progress in recent years, and its contents are many. The main ones that are closely related to the treatment of inhalation injury include respiratory function monitoring; oxygen therapy; establishment and management of artificial airway; and mechanical ventilation techniques, which are discussed below.  1, respiratory function monitoring: the purpose of monitoring respiratory function in patients with inhalation injury is to: (1) make a correct diagnosis and evaluation of the severity of the patient’s inhalation injury based on the status of the patient’s respiratory function.  (2) guide clinical treatment and timely adjustment of treatment according to the trend of respiratory function and changes in condition after treatment.  (3) To obtain timely alerts of sudden changes in the condition and take effective treatment measures.  (4) To help determine the indications for mechanical ventilation therapy and timely adjustment of ventilator working parameters.  The content of respiratory function monitoring is very rich, including general project monitoring; gas exchange parameters; respiratory mechanics parameters; hemodynamic monitoring; tissue oxygenation status monitoring; bedside imaging; pathogenic monitoring, etc. The simple and effective monitoring items should be selected according to the specific situation in the treatment of burn patients in groups, adhering to the principle of commonality as the main focus and individuality as a supplement, and unifying the monitoring items as much as possible to improve the efficiency of rescue work. Such as clinical indicators, blood gas analysis, pulse oximetry, transcutaneous oxygen and carbon dioxide partial pressure measurement, etc.. If conditions allow, then add other items as needed.  2, oxygen therapy: oxygen therapy is through the inhalation of different concentrations of oxygen higher than the oxygen concentration in the air, so that the partial pressure of alveolar oxygen (PA02) increases. In turn, it raises the PaO2 to finally achieve the purpose of correcting tissue hypoxia. Oxygen therapy can be divided into the following four categories: (1) Classification according to the degree of control of inhaled oxygen concentration (FiO2): ① Uncontrolled oxygen therapy: Fi02 does not need to be strictly controlled, and oxygen flow can be adjusted according to the needs of the disease to achieve the purpose of relieving hypoxemia. This method is suitable for patients without ventilatory disorders.  (2) Controlled oxygen therapy: FiO2: is strictly controlled, and ventilation such as positive airway pressure (CPAP) is used to achieve the purpose of oxygen therapy.  (2) Classification according to the level of FiO2: ①Low concentration oxygen therapy: refers to the oxygen therapy with FiO2: <30%.  (2) High concentration oxygen therapy: refers to the oxygen therapy with FiO2: >50%.  (3) Medium-concentration oxygen therapy: refers to the oxygen therapy with FiO2: ≥ 30%, and ≤ 50%.  (3) Classification according to the size of oxygen flow rate 1.Low flow rate oxygen inhalation: refers to oxygen inhalation with oxygen flow rate within 4L/min.  2.High flow oxygen absorption: refers to oxygen flow ≥ 4L/min oxygen absorption.  (4) according to the classification of air pressure ① atmospheric pressure oxygen therapy: refers to oxygen therapy under 1 atmosphere pressure.  ② Hyperbaric oxygen therapy: refers to oxygen therapy under more than 1 atmosphere pressure, that is, hyperbaric oxygen chamber treatment. This is a special method that requires the patient to be placed in an airtight hyperbaric chamber to absorb pure oxygen in a high-pressure environment so that PaO2; is extremely increased and the amount of physically dissolved oxygen in the blood is increased for the purpose of treating hypoxia.  The correct choice is based on the patient’s respiratory function monitoring and the specific equipment available at the medical institution at the time when treating a group of burn patients. Such as nasal cannula oxygenation, mask method oxygenation, tracheotomy or endotracheal intubation catheter oxygen administration, ventilator controlled oxygen therapy, etc. In oxygen therapy, we should pay attention to the side effects of oxygen therapy and the prevention methods. Especially to prevent the occurrence of oxygen toxicity. Prevention and treatment of oxygen toxicity: 1. There is no effective treatment for oxygen toxicity, and prevention is better than treatment. The degree of oxygen intoxication depends on the level of Fi02 and the length of time of oxygen inhalation. Under anesthesia, the duration of pure oxygen inhalation should be less than 24 hours. Fi02 should be controlled below 60% during oxygen therapy, and below 40% for newborns.  2.Close observation of PaO2, maintain the required PaO2, the lower the Fi02, the safer it is.  3.Intermittent high concentration oxygen intake can delay the occurrence of oxygen toxicity.  4.Some drugs can reduce the occurrence of oxygen toxicity: such as sedative, anticonvulsant and anesthetic drugs, vitamin E, reducing glutathione, ascorbic acid drugs, etc. It has been reported that the use of adrenocorticotropic hormone, hyperthyroidism, elevated body temperature, vitamin E deficiency, etc. can accelerate the occurrence of oxygen toxicity and should be noted.  5.For neonates, it is difficult to check blood gas by blood sampling, so the change of retinal blood vessel diameter can be monitored to guide oxygenation. If vasoconstriction is obvious, Fi02 should be reduced appropriately. 3, mechanical ventilation techniques overview: inhalation injury patients have varying degrees of respiratory insufficiency, pulmonary complications are quite common, and respiratory failure can occur throughout the course of the disease and endanger life. Respiratory failure due to inhalation injury has many etiologies and complex pathogenesis, but patients all exhibit inadequate effective ventilation, imbalance in the ratio of ventilation to blood flow, impaired gas diffusion, so that the body does not receive sufficient oxygen supply, resulting in tissue cell hypoxia, leading to damage to the peripheral organs.     4, the establishment and management of artificial airway: artificial airway is the catheter through the nose / mouth into the trachea or tracheotomy established by the gas channel. In the treatment of a group of casualties, the timing and indications of tracheotomy is a serious test of the knowledge and experience of the burn physician. The early appearance of airway obstruction in patients with inhalation injury is mostly caused by laryngeal edema, blockage of secretions, extensive bronchospasm or substantial lung injury, and there is a risk of asphyxiation if treatment is delayed. It is important to grasp the timing and perform tracheal intubation and tracheotomy in a timely manner. Adequate humidification of inhaled gas and nebulized inhalation therapy are extremely important to maintain the normal physiological function of the respiratory system. In addition, meticulous care such as turning, back patting and sputum aspiration should be done. If necessary, subfiber bronchial drainage and drug administration should be implemented to keep the airway open.  In conclusion, the application of respiratory function support techniques in the treatment of group burn patients is an indispensable technical tool for the successful resuscitation of patients with inhalation injuries. Every burn surgeon should pay attention to the progress in this field, combine the characteristics of group injuries, and apply the best treatment concepts and methods effectively in the clinical rescue work to achieve successful resuscitation work.