Low mean red blood cell hemoglobin concentration may be caused by drinking alcohol before the test, which leads to abnormal test results, in which case the test needs to be retested. If it is not due to the reasons mentioned above, it may be caused by microcytic hypochromic anemia, which requires prompt medical attention. The low average red blood cell hemoglobin concentration may be caused by eating too oily, high protein food and drinking a lot of alcohol before the test. Since alcohol in the blood will affect the test results, it is recommended to control the diet and avoid drinking alcohol in this case, and re-test the test again, and fast for 8 hours the day before the test, to make sure the accuracy of the test results. If the patient has microcytic hypochromic anemia, this can also cause low average red blood cell hemoglobin concentration, this disease includes iron deficiency anemia, bead protein production disorder anemia, iron granulocyte anemia and anemia of chronic disease and other diseases, this situation needs to be treated symptomatically according to the different types of diseases. For example, iron deficiency anemia can be treated with iron supplements such as ferrous sulfate and iron dextrose; dysglobinopoietic anemia can be treated with blood transfusions and surgery; ferrocytic anemia includes treatment with vitamin B6, bone marrow transplantation, and blood transfusions; anemia of chronic disease requires treatment of the underlying disease, blood transfusions, iron supplements, and other treatments. Low average red blood cell hemoglobin concentration is found to need to clarify the cause of the disease, and if necessary, follow the doctor’s instructions for treatment.