There are three main possibilities for chest pain when pressed, as follows: first, chest wall injury, mostly with a clear history of trauma, when external forces act directly or indirectly on the chest wall, causing chest wall tissue congestion, edema, acute inflammatory changes, chest pain and discomfort, and increased when pressed. Second, cystic hyperplasia of the breast, mostly seen in women aged 30-50, manifested as breast pain with hyperplastic nodule-like changes, with bilateral breasts, and the degree of pain related to the menstrual cycle. Thirdly, acute mastitis, which occurs in lactating women, is characterized by redness, swelling, heat and pain in the breasts, and can be accompanied by the formation of fluctuating breast lumps. When there is pain in the chest when pressed, if you can exclude that it is caused by trauma to the chest wall, you should go to the regular hospital breast surgery or general surgery in time to clarify the cause of the pain and carry out reasonable treatment under the guidance of a specialist, the pain can mostly be relieved and will not cause serious clinical consequences.