The disease tuberous sclerosis is an autosomal dominant disease. Its main manifestations are the presence of seizures or intellectual condition, and some cases of rash on the face. Most of the cases are around the age of 10 years old, if there is brain damage generally cerebral cortex, so it will cause some neurological manifestations. In the skin manifestations are mainly angiofibromas of the face, on the sides of the nose or around the eyes or these places can be seen yellowish papules, there are also some hemangiomas around the nails will appear. There are also hemangiomas around the nails. There are some raised patches on the skin or café au lait spots, and some of them have mental retardation and epilepsy. There is no good treatment for this disease, and if there is epilepsy, it can be treated with appropriate surgery or therapy. If the skin is superficial, cosmetic aspects may require lasers, which can provide temporary relief.