Toothache is mostly seen in pulpitis, periapical periodontitis, periodontitis, acute gingival papillitis, pericoronitis of wisdom teeth, etc. Specifically as follows: 1, pulpitis is the bacterial infection destroys the tooth tissue to form caries, and fails to control the caries further to the deep development in time, infecting the pulp tissue to form pulpitis, causing pain; 2, periapical periodontitis is the pulpitis is not treated in time, the bacteria break through the apical hole into the apical area, causing the periapical tissue infection; 3, periodontitis is the poor oral hygiene, the tooth retains the plaque, the plaque calcification forms the calculus The two together stimulate the periodontal tissue, resulting in gingivitis, periodontal pocket formation, alveolar bone resorption, tooth loosening, and pain in the teeth when the periodontal tissue is infected with acute inflammation; 4, acute gingival papillitis is caused by food embedding between the teeth, failure to clean in time or improper cleaning with toothpicks to damage the gums; 5, wisdom tooth pericoronitis is when the wisdom tooth eruption is incomplete or completely unable to erupt, and the surrounding tissue is inflamed. In addition, there are some other causes of toothache, it is recommended to seek medical attention in time to identify the cause of toothache and then treat it accordingly.