Axillary lymph node nodules may be caused by inflammation of the lymph nodes, connective tissue disease, lymphoma, secondary axillary malignant tumors and other causes. Treatment measures should be chosen according to the specific causes. 1. Inflammation of lymph nodes: Inflammation of lymph nodes is usually caused by infections in the upper limbs, shoulders and chest wall. Patients can use cefaclor, amoxicillin and other antibiotics under the guidance of the doctor’s advice to fight infection. For lymph node enlargement caused by tuberculosis infection, it is also necessary to take isoniazid, rifampicin, ethambutol and other drugs. 2. Connective tissue disease: according to the condition, under the guidance of the doctor for treatment, commonly used drugs are glucocorticosteroids, such as prednisolone and so on. 3. Lymphoma: when diagnosed as lymphoma invading the armpit, simple radiation therapy can be given if it is in early stage, and chemotherapy with abvd program or even bone marrow transplantation can be used if it is in middle or late stage. 4. Secondary axillary malignant tumors: lymphatic metastasis of malignant tumors can invade the axillary lymph nodes, which can be treated with combined surgery, radiotherapy, chemotherapy and targeted drugs for the primary tumor. Therefore, it is recommended that patients who have lymph nodes must seek medical treatment in time. If necessary, do pathological examination to clarify the nature, so as to have targeted treatment.