High quantitative D-dimer is usually indicative of hypercoagulability, e.g., physiologic changes, thrombophilia, etc., and requires early identification of the cause. Quantitative D-dimer test is a commonly used blood test to quantify D-dimer in the body. When D-dimer quantification is high, it usually indicates a hypercoagulable state in the body, and is therefore often used as an auxiliary indicator to determine whether there is thrombosis in the body. Higher results can be caused by changes in physiological status, for example, pregnant women will be in a hypercoagulable state due to the influence of the fetus, and the hypercoagulable state will gradually return to normal with the end of pregnancy, so there is no need to be overly nervous, and close observation is sufficient. When thrombotic diseases occur, such as cerebral infarction, pulmonary embolism, lower extremity venous thrombosis, etc., it will cause high D-dimer quantification. High D-dimer quantification requires timely relevant auxiliary examinations, clear diagnosis and early intervention to avoid delaying the best time for treatment.