Coughing up blood requires the use of chemotherapeutic agents such as metronidazole, budesonide, penicillin, isoniazid, cisplatin, etc., depending on periodontitis, rhinitis, pneumonia, tuberculosis, and lung cancer, respectively. 1. Periodontitis, which can cause bleeding gums and hemoptysis when blood is coughed up with sputum, can be treated with metronidazole. 2. Rhinitis, which can cause bleeding from the nose and hemoptysis when the blood is backed up, generally use budesonide nasal spray, natural sea salt water and other nasal spray to improve rhinitis, combined with bleeding from the nose, can be localized pressure, cold compresses, combined with vitamin E ointment application. 3. Pneumonia, due to lung infection, bronchial dilatation combined with infection, can damage the bronchial mucosa leading to bleeding, can use penicillin and other broad-spectrum antibiotics for anti-infection treatment. 4. Tuberculosis, hemoptysis is a typical symptom of tuberculosis, which can be treated with anti-tuberculosis drugs such as isoniazid. 5. Lung cancer, lung cancer itself can bleed. Combined with the type and stage of the tumor, it can be treated with chemotherapy drugs such as cisplatin, radiotherapy and surgical resection. The specific cause of the disease should be clarified after medical examination, and the drugs should be used according to the doctor’s prescription.