The symptoms of headache of pituitary tumor of brain, in general, belong to a gradually aggravating tendency, and are mainly head swelling and pain, bilateral temporal and forehead pain, like this, in many cases are the situation of pituitary tumor of brain. However, it must be noted that pituitary tumor of the brain has headache symptoms, but more often there will be other accompanying symptoms, such as blurred vision, visual field defects and other manifestations, and if it is a pituitary tumor with endocrine function, there may be more obvious other symptoms, such as lactation, menstrual disorders, even menopause, and men’s decline in sexual function and so on, or it is the pituitary tumor of growth hormone type. Or the growth hormone type of pituitary tumor may also cause the enlargement of the knuckles at the end of the limbs, and these accompanying symptoms are more able to determine that the tumor is a pituitary tumor of the brain, so it is not only a symptom of headache, but also accompanied by other manifestations.