Due to individual differences, there is no “fastest” way to reduce swelling in the legs. It is necessary to choose a solution according to the cause of the swelling. Clinically, it is generally considered to be related to kidney disease, hypoproteinemia, trauma, and deep vein thrombosis of the lower limbs. Treatment includes medication, surgery, etc. 1. Kidney disease: Swelling caused by nephritis is mainly treated with diuretics, such as hydrochlorothiazide tablets, furosemide tablets, torasemide tablets, spironolactone tablets and so on. 2. Hypoproteinemia: patients with hypoproteinemia have reduced plasma albumin and lower osmotic pressure, resulting in leg swelling. Clinical treatment is mainly through protein supplementation, such as supplementation of serum albumin, whey protein isolation. 3. trauma: if the patient’s legs are subjected to external extrusion and collision. This causes the local subcutaneous tissue cells to bleed and rupture. The symptoms of leg swelling. Clinical mainly through cold wet compresses to relieve symptoms, can also be elevated to promote venous lymphatic return. 4. Deep vein thrombosis of the lower limbs: bedridden deep vein thrombosis of the lower limbs causes leg swelling, which requires ultrasound examination to confirm the diagnosis and the use of drugs (such as warfarin) or even surgical treatment (venous thrombosis) according to the situation. All of the above medications should be used under doctor’s guidance to avoid self-medication, and it is recommended to consult a doctor in time to clarify the cause of the disease and carry out targeted treatment or therapy with the help of the doctor.