High absolute neutrophil values may be pathologically elevated, such as in bacterial infections, tissue injuries, hematologic disorders, etc., or physiologically elevated, such as after strenuous exercise.
Pathological elevation is common in the following cases:
1. Diseases caused by bacterial infections, such as pneumonia, acute gastroenteritis, local skin infections (boils, carbuncles, etc.), etc., the absolute value of neutrophils increases to play the role of anti-inflammatory, and the absolute value of neutrophils can be gradually restored to normal after active anti-infective treatment.
2. Tissue injury: major surgery, trauma, traumatic injury; acute myocardial infarction, acute cerebral infarction, pulmonary embolism and other diseases, there will be varying degrees of stress neutrophil absolute value of neutrophils will be increased, can gradually return to normal, but it takes a longer time.
3. When acute myeloid leukemia or chronic granulocytic leukemia occurs, the absolute neutrophil value will also be elevated, but the magnitude of the elevation is very large, and it can often be greater than 100*10^9/L. The absolute neutrophil value will also be elevated in neonates.
Physiological elevation is seen in newborns, middle and late pregnancy, and a mild increase in absolute neutrophil value may also occur after strenuous exercise, which is temporary and can return to normal on its own.
If the absolute neutrophil value is elevated, it is necessary to consult a doctor in time to identify the specific cause of the disease and receive targeted treatment.