Diarrhea may be caused by indigestion, intestinal inflammation, and intestinal flora imbalance. Diarrhea leading to anal pain may be caused by the stimulation of defecation, perianal lesions. It is recommended to pay attention to local care and give anti-infective, antidiarrheal and probiotic drugs for the primary disease to regulate, which can help relieve the symptoms. 1. Indigestion: poor digestion and absorption causes diarrhea and abdominal pain, it is recommended to eat regularly, avoid greasy fried, barbecue, spicy stimulating food intake. Can follow the doctor’s advice to give digestive enzymes, bifidobacteria to regulate, relieve indigestion, diarrhea. 2. Enteritis: affected by various factors, resulting in acute and chronic inflammation of the intestinal mucosa, intestinal peristalsis, causing diarrhea. If bacterial infection can be given norfloxacin, levofloxacin and other anti-infective treatment. Also pay attention to the perianal care, reduce the local stimulation. 3. Intestinal flora imbalance: the increase of harmful intestinal bacteria causes diarrhea, and the repeated local stimulation during defecation leads to anal pain. Bifidobacteria and lactobacilli can be given as prescribed by the doctor to regulate, which can effectively relieve the symptoms. 4. Perianal lesions: fecal mucus during diarrhea causes irritation to the perianal area, causing eczema and dermatitis, resulting in local pain. It is recommended to treat the primary disease, wash the affected area with warm water every night, apply tacrolimus ointment externally, if necessary, with vitamin B, vitamin C, methylcobalamin and other drugs to assist in the treatment. Diarrhea anal pain, there may also be a variety of other reasons, it is recommended that the patient to the hospital gastroenterology department, under the guidance of the doctor for the treatment of the primary disease, to alleviate the symptoms of diarrhea, the pain will gradually ease.