There is no difference between lacosamide and levetiracetam in terms of which is more effective or less effective, and the appropriate medication should be chosen based on the patient’s condition. Lacosamide is indicated as adjunctive therapy for the treatment of partial seizures with or without secondary generalized seizures in patients with epilepsy who are greater than or equal to 16 years of age; whereas levetiracetam is indicated for the adjunctive treatment of partial and inspired generalized seizures, and can also be used as adjunctive therapy for epilepsy in children (4 to 16 years of age). It is important to note that there are no clear contraindications to lacosamide, but patients may experience adverse reactions such as dizziness, headache, and vomiting after taking it. And levetiracetam is prohibited for those who are allergic to levetiracetam, pyrrolidone derivatives, or any other ingredients, and patients may experience adverse reactions such as drowsiness, fatigue and dizziness after taking it. It is recommended that patients should use the drug under the guidance of a doctor, do not use it without authorization to avoid delay.