Whether an 80-year-old can still have pericardial effusion surgery depends on the amount of pericardial effusion as well as the patient’s physical fitness, etc. If the amount of fluid is large, surgery is recommended. If the amount of fluid is small and the patient is not physically able to tolerate it, surgery may be withheld. 1. Surgery is possible: For elderly patients with large amount of pericardial effusion who are able to tolerate surgery, pericardiocentesis should be performed in a timely manner if obvious symptoms of pericardial tamponade are present, in order to alleviate the symptoms and save lives. 2. Temporary surgery: For elderly patients with small amount of pericardial effusion who cannot tolerate surgery, if there are no obvious symptoms such as dyspnea, they can be treated conservatively for the time being by using diuretic drugs such as furosemide, spironolactone, and thiazides under the guidance of physicians. Elderly patients with pericardial effusion are advised to actively go to regular hospitals to find out the cause of the disease and early treatment, so as not to delay the condition and cause life-threatening injuries. The above drugs need to be used in a standardized manner under the guidance of a doctor.