Low fluorescence reticulocyte ratio is the percentage of reticulocytes that appear to stain with low fluorescence intensity as a result of nucleic acid fluorescence staining of reticulocytes.
Reticulocytes are immature erythrocytes between late juvenile and mature erythrocytes, staining the nucleic acid substances in the cytoplasm of the cells with nucleic acid fluorescent dye can show three fluorescence intensities: high, medium and low, and the percentage of reticulocytes stained with low fluorescence intensity is the percentage of reticulocytes with low fluorescence, i.e., low-fluorescence reticulocytes.
The higher the fluorescence of reticulocytes, the more immature they are, and they can be used as a primary screening indicator for certain anemias. The percentage of hypofluorescent reticulocytes is lower than normal in thalassemia minor, and increases with the degree of anemia. The percentage of hyperfluorescent reticulocytes, moderately fluorescent reticulocytes, and immature reticulocytes increases with the degree of anemia. It is necessary to go to the hematology department of the hospital in time.