Albumin transaminase 45.1 U/L is mildly high, which may be physiologically high or related to diseases of the liver and gallbladder. However, the elevation of AST does not indicate the seriousness of the disease, but needs to be combined with other indicators to make a comprehensive judgment. 1. Physiological high: for example, eating high-fat food, overworking, staying up late or doing strenuous exercise, causing mildly high AST, which is not serious. This situation is not serious. Generally through changing the diet structure, more rest can gradually decline. If necessary, follow the doctor’s advice to add liver-protecting drugs such as silymarin and other treatments. 2. Alcoholic liver disease: It is necessary to strictly prohibit alcohol and give liver-protecting and enzyme-lowering medicines, such as reduced glutathione and dicyclomine, etc., which can gradually make the GC aminotransferase return to normal. 3. Viral hepatitis: if the infection of hepatitis B virus causes mildly high ghrelin, anti-viral treatment such as lamivudine and entecavir can be given, and at the same time auxiliary use of liver-protecting medicines such as silymarin can gradually make ghrelin decrease. Critically speaking, the elevation of the single index of AST does not indicate whether it is serious or not, for example, in patients with liver failure, AST can even be reduced to the normal range. A combination of other indicators is needed. When the patient has a biliary tract obstructive disease, such as sclerosing cholangitis, biliary system tumors and other diseases, it will cause cholestasis, which can also lead to an increase in serum alanine aminotransferase. It is recommended to consult a doctor in time to find out the cause and follow the doctor’s instructions for treatment, not self-medication.