The root of the thigh, i.e. the groin. Enlargement of lymph nodes in this area is mostly due to lymphadenitis, tumors and other causes, and should be treated according to the cause. 1. Lymphadenitis: when the leg, nearby perineum and other places due to trauma, bacterial infection and other factors, can lead to the emergence of lymphadenitis, which can be manifested as localized lymph node enlargement, accompanied by pain, lymph nodes have tenderness, mobility is still possible, and the surface is smooth. For lymphadenitis caused by infection of nearby tissues, different medications can be taken depending on the pathogen. For bacterial infection, amoxicillin, cefaclor, levofloxacin and other antibiotics can be taken; for lymphadenitis caused by fungal infection of the skin, amphotericin B, mycotoxin and other drugs can be taken; for viral infection, acyclovir, ribavirin and other drugs can be taken. 2. Tumor: when lymph node enlargement is caused by lymphoma or cancer lymph node metastasis, it should be clearly diagnosed and then timely operated according to the primary tumor, radiotherapy and other active anti-tumor treatment. When lymph node enlargement occurs, it should be diagnosed and treated in time so as not to delay the condition, and the medicine should be applied under the guidance of doctor.