Acute thrombocytopenic purpura

Acute thrombocytopenic purpura, also known as acute idiopathic or immune thrombocytopenic purpura, is particularly a thrombocytopenia with normal bone marrow and lack of other causes of thrombocytopenia, manifested by symptoms such as bleeding from the skin and mucous membranes. The disease mostly occurs in viral infections or recovery from upper respiratory tract infections, such as rubella, measles, chickenpox, mumps virus and other pathogens. The pathogenesis may be a cross-reaction between antigen-antibody complexes, including viral antigens, and platelet Fc receptors, or autoantibodies produced by viral antigens, and platelet membranes, damaging platelets. The treatment principle of acute thrombocytopenic purpura is to reduce the destruction of platelets and increase the production of platelets, the main treatment methods are as follows: 1, general treatment: prevent all kinds of trauma, bed rest if serious, avoid eating foods that inhibit platelet aggregation, such as black fungus, garlic, onion, etc., and do not take platelet inhibiting drugs, such as aspirin, etc.; 2, drug treatment: such as platelet-raising drugs 2, drug therapy: such as platelet-raising drugs, glucocorticoids, etc. Platelet-raising drugs can promote the production of platelets, commonly used drugs such as Etripopat and Romistatin. Glucocorticoids can reduce the destruction of platelets, suitable for patients with severe symptoms, commonly used drugs are dexamethasone, prednisone, etc.; 3, intravenous infusion of platelet preparations: can quickly replenish the number of platelets in the blood, suitable for patients with severe bleeding; 4, surgery: splenectomy can reduce the destruction of platelets by the spleen, suitable for patients with poor effect of glucocorticoids and other drugs, accompanied by an enlarged spleen.