Fistula after necrosectomy of the small intestine can be self-healing, but it is not completely unconditional. Intestinal fistula can usually be completely cured, including conservative treatment and surgical treatment; the so-called self-healing generally refers to the conservative treatment relative to re-operation, the process is more complex, usually not completely unconditional self-healing; by the location of the fistula, size, single or multiple, drainage, infection, nutritional support and other issues have a greater impact. 1. single, smaller intestinal fistula: need fasting and rehydration, anti-inflammatory and anti-infection, acid suppression, parenteral nutrition, maintenance of water-electrolyte balance, etc., double catheter flushing and drainage, healing can be resumed; jejunoileal fistula average self-healing time of about 3-4 weeks, ileocolic fistula of about 4-6 weeks. 2. intestinal fistula or multiple fistula: easy to cause peritonitis, conservative treatment effect is poor, most need to re-open the abdomen to explore the surgical treatment; postoperative also need to pay attention to strengthen the anti-infective, anti-inflammatory acid suppression, parenteral nutrition, rehydration to maintain water-electrolyte balance and other symptomatic treatment. Intestinal fistula need to closely observe the changes in the condition, standardized treatment, if necessary, timely surgery, follow the physician’s advice.