Epilepsy is a chronic brain disorder characterized by recurrent and transient central nervous system malfunctions due to transitional neuronal discharges in the brain. There are many factors that trigger this disease, among which psychological factors play a considerable role. Understanding the psychological state of patients. It is important to understand the psychological status of the patient, so that they can be targeted to help them live a reasonable treatment and enjoyable life. Patients with epilepsy have the following physical characteristics: (1) Depression This is a pathogenic factor in itself. Once you have epilepsy, the features of melancholy are more obvious. Increased psychological burden, sullenness and moodiness can, over time, lead to more serious mental depression, causing painful life and psychological burden to the patient and affecting the therapeutic effect. (2) Low self-esteem Common causes are twofold: one is the patient himself. Because seizures do not distinguish time. Regardless of the location, occasion, seizures slightly more. Patients have formed a pathological psychology, resulting in a serious inferiority complex, the second is social pressure, living around the affected person, intentionally or unintentionally caused psychological harm to patients. In addition, social discrimination brings mental pressure to the patient. Sometimes the excessive care and attention from family members and people around the patient may also cause the patient to have a low self-esteem. (3) Loneliness Some patients realize that they are an epileptic patient and work. Some patients realize that they are an epileptic, and that they have to be restricted in life and study, and cannot be like normal people. So they fall into loneliness and do not want to be with everyone. They do not want to participate in group activities. Especially in adolescent patients, the feeling of loneliness is more intense. (4) Pessimism Due to the existence of the above characteristics. Patients are extremely traumatized, which is a cause of pessimism. Epilepsy is a difficult disease to treat. Long-term treatment has a serious impact on the patient’s body and mind. It shakes their confidence to overcome the disease. It is easy to produce pessimistic and desperate psychology. In short, many psychological factors that can cause aggravation of epileptic seizures. Therefore, psychotherapy is very important in the treatment of epilepsy. Psychotherapy is psychiatric treatment. It is the application of psychological principles and methods, techniques to improve the patient’s symptoms, to achieve the purpose of treating the disease. It generally uses mental comfort, support, persuasion, reassurance, guidance and environmental adjustment for the patient. They are also inspired, induced, educated and helped to understand the disease, the causes and symptoms of the disease. Raise their level of awareness. Increase the causes and symptoms of the disease cure. Increase their level of awareness. Increase confidence in the cure. Promote the recovery of the disease. There are many modern methods of psychotherapy, commonly used are cognitive therapy, individual and group psychotherapy, suggestion therapy, hypnotherapy, behavior therapy and biofeedback therapy. In summary, psychological factors play a very important role in the treatment of epilepsy. In addition to the correct use of drugs. In addition to relying on social and family help, patients can also rely on psychotherapy. In addition to relying on social and family help, patients should have a good psychological profile. The patient should also have good psychological quality. The patient should face the reality, actively cooperate with the doctor, acquire the necessary knowledge about his or her condition, and master the characteristics of his or her seizures and the triggers that may cause them. Take the initiative to accept all treatments in the treatment process to effectively control the attacks. In order to achieve both physical and psychological health.