If a woman has edema before menstruation that leads to weight gain, it is considered that it may be a physiological manifestation because the ratio of estrogen and progesterone is imbalanced, and a deficiency of progesterone or a decrease in tissue sensitivity to progesterone and a relatively high level of estrogen may cause significant water and sodium retention and lead to weight gain. For women who gain weight before menstruation and whose edema is not obvious, no treatment is needed. The edema performance will be relieved naturally after the menstruation clears and will not cause any adverse effects on the woman’s body. If a woman usually does not have edema before menstruation and suddenly develops severe edema before menstruation, not only edema of the eyelids, but also edema of both lower limbs, it may not be a normal performance and is considered to be caused by diseases of liver function and kidney function, such as acute nephritis or nephrotic syndrome.