Acne is a chronic inflammatory skin disease of the sebaceous gland unit of the hair follicle. It can be treated comprehensively through general treatment, topical medication, systemic medication, and phototherapy. 1. General treatment: During the period of acne, it is important to use water or suitable cleansing products to remove excessive oil, flakes and bacterial mixtures from the skin surface. Avoid squeezing or scratching the lesions with your hands; appropriately limit the intake of high glycemic index foods, such as candies, cakes and milk. 2. Topical medication: patients with mild cases are only treated with topical medication. (1) Retinoic acid: such as common 0.1% adapalene gel, tazarotene, is currently the first line of treatment for mild acne, during the use of some patients may appear mild skin irritation, such as localized erythema, flaking, etc., it is recommended to use a small range of low concentration. (2) Benzoyl peroxide: After topical application to the local skin, it can release new ecological oxygen and benzoic acid, which can play a role in killing Propionibacterium acnes and dissolving acne. A small number of patients may experience mild skin irritation, and it is recommended to use it in a low concentration and in a small range. 3. Systemic drugs: such as isotretinoin, can inhibit sebaceous secretion of sebaceous glands, regulate the keratinization of sebaceous ducts of hair follicles as well as improve the anaerobic environment of hair follicles, but it can lead to adverse reactions such as dryness of the lips and mouth and flaking, and has a teratogenic effect, and pregnancy can only be conceived after stopping the drug for three months. 4. Phototherapy: LED blue light or red light can be used to treat mild to moderate acne lesions, and intense pulsed light can be used to reduce the red marks of acne. Specific treatments should be combined with the patient’s specific condition and carried out under the guidance of a specialized doctor.