Double lung fibrosis is an imaging manifestation of the lung, lung CT shows grid-like or honeycomb hypointense shadow, accompanied by bronchial dilatation, vascular thickening, while the alveoli are translucent shadow, can be due to infectious or non-infectious factors, it is recommended to seek medical differential diagnosis after active treatment.1, infectious factors: due to bacteria, virus, Mycobacterium tuberculosis, mycoplasma, chlamydia and other infections, alveolar mucosa appears The alveolar mucosa becomes congested and necrotic, resulting in damage to the alveolar tissue, allowing fibroblasts to proliferate and deposit in the interstitial space of the lung, eventually forming bilateral lung fibrosis. Clinical anti-infective treatment is the main focus, such as bacterial infection, treatment can be applied to cefixime, cefuroxime sodium, penicillin and other antibiotics, viral infection with ganciclovir, ribavirin and other antiviral drugs, mycoplasma infection with azithromycin, erythromycin and other macrolides, tuberculosis for Mycobacterium tuberculosis infection, treatment with rifampin, isoniazid and other anti-tuberculosis drugs, while anti Fibrosis drugs, such as pirfenidone; 2, non-infectious factors: also known as secondary double lung fibrosis, such as long-term in a polluted environment, or the use of methotrexate, cyclophosphamide and other drugs, in addition to suffering from autoimmune diseases, etc., may lead to lung tissue inflammatory cells continue to gather, inflammatory substances continue to exude, deposition, and eventually cause the formation of fibrosis. It is necessary to pay attention to get out of the polluted environment, quit smoking and alcohol, and for double lung fibrosis caused by medication, the medication can be stopped or replaced with other medication without affecting the treatment of the original disease. For patients with autoimmune diseases, hormone and immune agent drug therapy, such as prednisolone acetate and gammaglobulin, are the main treatments. If symptoms such as cough and sputum are present, you can follow the doctor’s prescription to apply drugs to reduce sputum and asthma, such as amiloride hydrochloride and ipratropium bromide. There are many causes of pulmonary fibrosis and differences in treatment, so it is recommended to seek medical advice promptly. In addition, prevention of pulmonary fibrosis is important. Active drug treatment at the early stage of disease development can effectively avoid the continuous progression of pulmonary fibrosis, and at the later stage, we should pay attention to exercise, improve lung function and do more functional training in breathing.