Breastfeeding women with high total bile acid will have an effect on their babies if they take medication, and it is recommended that patients follow their doctor’s instructions for treatment. Patients with high total bile acid should not breastfeed because high total bile acid suggests that the patient may have liver and gallbladder diseases, such as cholecystitis, hepatitis, etc., which may lead to a decrease in the quality of milk, which is detrimental to the baby’s health if breastfeeding is carried out at this time. Moreover, patients with high total bile acids taking bile acid-lowering drugs may enter the baby’s body through breast milk, and it is recommended that women in the period of medication should not breastfeed, so as not to have adverse effects on the baby. When the patient is breastfeeding, found that the total bile acid is high, it is recommended to go to the hospital in a timely manner, under the guidance of a professional physician for treatment, in order to avoid adverse consequences.