Children with red rashes around the mouth can be considered to be skin allergies, eczema, viral infections, etc.; the overall treatment includes daily care, medication; parents need to consult a doctor in time and take targeted treatment according to different diseases. 1. Skin allergy: If the child has red spots, pimples, and bumps around the mouth, accompanied by itching, it can be considered as skin allergy. For treatment, parents need to find and avoid allergens, wash the affected area in time and keep it dry and clean. Children can use topical glycerine lotion, zinc oxide ointment, etc. to relieve itching, and glucocorticosteroids (hydrocortisone butyrate cream, etc.) can be used if the inflammation is severe; or oral antihistamines (such as loratadine, etc.) can be used for anti-allergy treatment. It should be noted that children often lick the lips, drooling and other causes of perilabial slobber rash also belongs to this type of disease. 2. Eczema: If the affected area shows erythema, edema, pimples and so on, it can be considered as eczema. Treatment, parents need to find and eliminate the cause of the disease; topical glycerine lotion, etc., severe inflammation can be used topical glucocorticosteroid cream, calcium-modulated neural phosphatase inhibitors (such as pimecrolimus cream), etc.; or oral antihistamine drugs such as loratadine, accompanied by a wide range of infections can be given antibiotic treatment (cefadroxil, etc.). 3. Viral infection: if the affected area is burning, cluster blisters, etc., viral infection (such as herpes simplex virus) can be considered; for treatment, antiviral treatment (such as topical acyclovir cream) is needed, and secondary infection can be treated with ointment such as Bactroban. Parents are advised to take their children to regular hospitals for consultation, identify the cause of the disease, and follow the doctor’s instructions for treatment.