Side effects of Oxymetazoline Hydrochloride Spray include drug rhinitis, allergic reactions, and headaches. This drug is contraindicated in people who are allergic to it, and patients with high blood pressure and coronary heart disease should use the drug with caution. Frequent use of Hydroxymetazoline Hydrochloride Spray is prone to rebound nasal congestion, which can also lead to drug rhinitis if the patient uses the drug for a long period of time. In addition, if patients are allergic to the components of hydroxymetazoline hydrochloride spray, they may experience allergic reactions such as sneezing, nasal itching, and difficulty in breathing after using the drug. In addition to this, some people may experience side effects such as headache, increased heart rate, dizziness, burning or pins and needles sensation in the nasal passages, and dryness of the nasal mucosa after using Oxymetazoline Hydrochloride Spray. Hydroxymetazoline Hydrochloride Spray is prohibited for people who are allergic to the drug treatment, in addition, patients with hypertension, coronary heart disease, hyperthyroidism, diabetes and other diseases should be careful with Hydroxymetazoline Hydrochloride Spray. It is recommended that hydroxymetazoline hydrochloride spray be used under the guidance of a pharmacist or under the guidance of the instructions, and hydroxymetazoline hydrochloride spray is contraindicated in patients with atrophic rhinitis and nasal dryness. In addition, pregnant women, lactating women, children under 3 years old are prohibited to use hydroxymetazoline hydrochloride spray. In case of discomfort, please seek medical advice and use the drug under the guidance of a physician.