New Year’s Eve, due to the cold weather and friends and family gatherings, drinking, poor rest, emotional excitement and other prone to myocardial infarction in patients with coronary heart. If you have hypertension, diabetes and coronary heart disease base patients, after the following performance to be highly alert to acute myocardial infarction, the wisest approach is to seek medical attention as soon as possible. 1, pain: is the first and most prominent symptom of acute myocardial infarction, the typical site is behind the sternum until the pharynx or in the precordial area, radiating to the left shoulder, left arm. The pain is sometimes in the upper abdomen or at the glabella, while the posterior part of the lower sternum is often suffocating and uncomfortable, or accompanied by nausea and vomiting, commonly associated with inferior wall myocardial infarction. Atypical sites include pain in the right chest, jaw, neck, teeth, rare head, lower thighs and even toes. The nature of the pain is cramp-like or pressure pain, or a tightening or burning pain, often accompanied by irritability, sweating, fear, or a sense of near death. The duration is often greater than 30min, or even up to 10 hours, rest and nitroglycerin generally can not relieve. 2. Systemic symptoms: mainly fever, accompanied by tachycardia, increased white blood cells and increased erythrocyte sedimentation rate, etc., caused by the absorption of necrotic material. It usually appears 24-48h after the onset of pain, and the degree is often positively correlated with the extent of infarction. The body temperature is usually around 38℃, rarely exceeds 39℃, and lasts for about 1 week. 3. Gastrointestinal symptoms: When the pain is severe, it is often accompanied by frequent nausea, vomiting and epigastric distension, which is related to the stimulation of the vagus nerve by the necrotic myocardium and reduced cardiac blood output and insufficient tissue perfusion. Intestinal distention is also not uncommon. In severe cases, eructation may occur. 4, arrhythmia: seen in 75%-95% of patients, mostly occurring within 1-2 weeks of onset, and most common within 24h, may be accompanied by weakness, dizziness, fainting and other symptoms. Ventricular arrhythmias are the most common, especially ventricular premature beats. If ventricular premature beats are frequent (more than 5 beats/min), occur in pairs or in short bursts of ventricular tachycardia, are multiple or fall in the vulnerable phase of the previous beat (RonT), they often indicate impending ventricular tachycardia or ventricular fibrillation. Ventricular fibrillation at onset in some patients can cause sudden cardiac death. Accelerated ventricular autonomic rhythm also occurs from time to time. Various degrees of atrioventricular block and bundle branch block are also common, and in severe cases, complete atrioventricular block may occur. Supraventricular arrhythmias are less common and occur more often in patients with heart failure. Anterior wall myocardial infarction is prone to ventricular arrhythmias; inferior wall myocardial infarction is prone to atrioventricular block; anterior wall myocardial infarction with atrioventricular block indicates extensive infarction and is often accompanied by shock or heart failure, so the situation is serious and the prognosis is poor. 5, hypotension and shock: blood pressure commonly decreases during the painful period, and without the manifestation of microcirculatory failure can only be called a hypotensive state. If the pain is relieved and the systolic blood pressure is still lower than 80 mmHg, the patient is agitated, pale, skin is cold, pulse is thin and fast, sweating profusely, urine volume is reduced (<20 ml/h), mental retardation, or even fainting, it is a sign of shock. Shock mostly occurs within a few hours to 1 week after the onset of the disease and is seen in 20% of patients. It is mainly cardiogenic, caused by extensive myocardial necrosis (more than 40%) and a rapid decrease in cardiac blood output, with peripheral vasodilatation caused by neurological reflexes as a secondary factor, and in some patients, blood volume deficiency is also involved. Severe shock can die within hours, usually lasts for hours to days, and can recur. 6, heart failure: the incidence of 30%-40%, when the general scope of left ventricular infarction has been > 20%, for the infarction after the myocardial contraction force is significantly weakened, ventricular compliance is reduced and myocardial contraction is not coordinated due to. It is mainly acute left heart failure, which can occur within the first few days of onset or during the improvement phase of pain and shock, or sudden onset of pulmonary edema as the initial manifestation. Patients present with chest pressure, asphyxial dyspnea, telangiectatic breathing, coughing, coughing up white or pink frothy sputum, sweating, cyanosis, and irritability, and in severe cases, right heart failure manifestations such as jugular vein anger, hepatomegaly, and edema. In right ventricular myocardial infarction, right heart failure may appear at the beginning with a drop in blood pressure.