The following possibilities should be considered for numbness in the hands and feet at night: 1. neurogenic cervical spondylosis, it is recommended to see a neurologist at the hospital and perform a cervical spine MRI for a clear diagnosis. 2. peripheral neuropathy, such as diabetic peripheral neuropathy causing the above discomfort, it is recommended to see a doctor at the hospital to perform blood glucose monitoring and electromyography of the extremities for a clear diagnosis. 3. If a patient has numbness in the hands and feet accompanied by a loss of strength, it is also necessary to consider neurological demyelination diseases, such as Grinbarrhe and other diseases that cause the above discomfort. The specific cause of the numbness of the hands and feet, must go to the hospital to see a doctor to perform relevant tests to be able to clarify.