Urine protein + means that there is protein in the urine. Under normal circumstances urine protein is negative is not a plus sign, urine protein + indicates that there is protein in the urine. The causes include physiologic and pathologic causes. Physiological causes such as fatigue, strenuous exercise, etc., usually when the triggering factors are eliminated, urine protein can gradually return to normal. Pathological causes such as acute and chronic nephritis and certain chronic diseases caused by renal damage and other laboratory urine may appear urine protein +, at this time should actively treat the primary disease, such as the application of glucocorticoids such as prednisone and other immunosuppressive agents such as cyclophosphamide. At the same time regularly to the regular hospital review regular rest to avoid exertion. Laboratory results are abnormal, it is recommended to go to the regular hospital in a timely manner to consult the examination, clear cause of the targeted selection of appropriate drug therapy, avoid self-medication.