Non-steroidal anti-inflammatory drugs, blood circulation and blood stasis medicines, swelling medicines, dehydration and diuretics can be used to reduce swelling after knee surgery. After knee surgery, there will be localized swelling of the knee joint, which is a normal phenomenon. Generally speaking, elevating the affected limbs after surgery is conducive to venous return and promotes swelling, and some medicines can be chosen for treatment if necessary. 1. Non-steroidal anti-inflammatory drugs (NSAIDs): If there is localized inflammation and swelling in the knee joint after surgery, NSAIDs such as Celecoxib can be used in moderation to help relieve inflammation and eliminate swelling. 2. Drugs for activating blood circulation and removing blood stasis: such as Panax ginseng tablets for activating blood circulation can help accelerate blood circulation and reduce local exudation, thus reducing swelling. 3. Anti-swelling medicines: such as Mai Zhi Ling, which can promote the swelling to subside. 4. Dehydration and diuretic drugs: such as mannitol, etc., through the diuretic effect, can reduce the whole body as well as local edema. However, it should be noted that if swelling and pain occur in the foot and calf or thigh after knee surgery, it should be promptly ruled out whether deep vein thrombosis of the lower limb is formed. Post-operative swelling of the knee joint is recommended to be treated under the guidance of a specialist, and self-medication should be avoided to avoid adverse consequences.