Patients with abdominal tuberculosis can be treated with anti-tuberculosis drugs, and some require peritoneal puncture for fluid drainage. After an attack of intestinal tuberculosis, there is a certain possibility of metastasis in the abdominal cavity, resulting in abdominal tuberculosis, which is mainly manifested by abdominal distension, fluid accumulation in the abdominal cavity, nausea, vomiting, hot flashes, and night sweats. The main anti-tuberculosis treatment is the use of quadruple therapy. The common drugs are isoniazid, ethambutol, pyrazinamide, and rifampin, and the combination of these drugs can inhibit the reproduction of Mycobacterium tuberculosis in the body and kill Mycobacterium tuberculosis in the body, so that the purpose of curing abdominal cavity tuberculosis can be achieved. Many patients with abdominal tuberculosis also suffer from peritonitis, which can lead to a large amount of ascites. For people with severe ascites, the fluid can be drained from the abdominal cavity by means of laparotomy, and care should be taken not to drain too much at once to avoid a drop in blood pressure.